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There
is also the group of patients that
primarily present with hoarseness
and sore throat. Laryngo
Pharyngeal Reflux or LPR is
the designation given these
patients with predominantly throat
and upper respiratory symptoms. In
addition to hoarseness and sore
throat these patients have a
feeling of a lump in the throat,
too much mucous in the throat
secondary to sinusitis, chronic
cough, trouble swallowing and a
surprisingly large number of these
patients give a history of polyps
of the nose. Some patients with LPR
have a lot of heartburn while
others, about half of them, have
very little heartburn or only a
history of heartburn in the past
with loss of the heartburn
coinciding with the advent of the
predominantly upper respiratory
symptoms. LPR syndrome patients who have no history of heartburn are those who have only minute amounts of acid refluxing not sufficient to inflame the esophagus but able to irritate the vocal cords, pulmonary linings and upper respiratory passages. These mucous membranes or linings are much more sensitive to minute amounts of acid as compared to the esophageal mucosa. When
patients with LPR syndrome
give a history of many years of
heartburn that seems to have
subsided with the rise of the
upper respiratory symptoms, it is
not uncommon to find that the
lower esophageal mucosa has
changed into the ominous
precancerous Barrett esophagus. |
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